RE3 Remake
Resident Evil 3 Remake (RE3 Remake) Wiki Guide
NEST 2 Laboratory - Story Walkthrough
RE3 Remake | NEST 2 Laboratory - Story Walkthrough | Resident Evil 3 Remake - GameWith

Resident Evil 3 Remake | RE3 Remake
NEST 2 Laboratory - Story Walkthrough

Last Updated:

Learn how to clear the NEST 2 Laboratory in RE3 Remake (Resident Evil 3) in this walkthrough. This guide includes tips, boss fights, secret item location & more!

Table of Contents

Campaign Progression & Walkthrough

<< Previous MissionNext Mission >>
7. Underground Storage9. NEST 2 Facility (Ending)
Check Out The Story Mission Walkthrough List

NEST 2 Laboratory Quick Video Guide

Making The Vaccine Walkthrough

Making The Vaccine Walkthrough Chart

1After the cutscene with Tyrell, proceed to the room at the end of the corridor to access the Safe Room
2Proceed upstairs and enter the room down the hall. Interact with the computer to get the Flash Drive
3Head downstairs and use the Flash Drive on the locked door to open it
4Make your way up the stairs and access the terminal to get the Culture Sample
5Go back down and use the door to the Generator Room. Push the Generator to unlock the door
6Traverse the lab and use the lift to head to the upper floor. Enter the room and pull out the tray to get the Liquid Filled Test Tube
7Use the lift to make your way back. Kill the reanimated Hunter βs to unlock the door
8Return to the room where you found the Flash Drive. Combine the Liquid Filled Test Tube and the Culture Sample to get the Vaccine Base
9Interact with the large machine and use the Vaccine Base. The combination for the puzzle should be Mid, High, Low. Get the Vaccine
10Use the vent to escape. Crawl your way towards the lift

Get The Flash Drive

Open Locked Door With Flash Drive

Open Locked Door With Flash Drive

The locked door located in the first hallway can be accessed by taking a Flash Drive from the room in the 2nd floor. Note that you will be returning to this room later on for the Vaccine.

Check Out How To Get The Flash Drive!

4. Getting The Culture Sample

Evade Or Slow Down The Pale Heads

There will be a number of Pale Heads in this area. As they are pretty resilient against damage, momentarily shoot them down to advance. Try to evade them instead and conserve your ammo as much as you can. You can kill Pale Heads with a direct shot from the Magnum.

Check Out The Pale Head Guide Here!

7. Battling The Hunter β

Use Shotgun & Grenade Launcher

2 Hunter βs will burst out of their containers to attack you after you get off the lift. Use the Shotgun and the Grenade Launcher to quickly dispatch them.

Check Out The Hunter β (Beta) Guide Here!

9. Making The Vaccine Base

Laboratory Vaccine Puzzle Solution

Vaccine Puzzle Solution

Combine the Liquid Filled Test Tube with the Culture Sample to create the Vaccine Base. However, there is a puzzle that you must solve in order to make the Vaccine Base into a Vaccine. To solve the puzzle, set the three bars to Mid, High, Low.


NEST 2 Laboratory - Secret Item Location

NOTE: This section is currently a work in progress. Come back later for updates!

Item Location Map

Check Out All Item List

Campaign Progression & Walkthrough

<< Previous MissionNext Mission >>
7. Underground Storage9. NEST 2 Facility (Ending)
Check Out The Story Mission Walkthrough List>> Pt.8 Park ~ Dead Factory in RE3 Original

Resident Evil 3 (RE3) Remake Related Article

Go Back To The Top Page

Story Walkthrough

Useful Guide

Data Base & List

Other RE3 Related Guide

Trademarks are the property of their respective owners. Its licensors have not otherwise endorsed and are not responsible for the operation of or content on this site.

Have some feedback? Click here

Your feedbacks will be checked by our staffs and will be attended to accordingly. Please be advised that we may not reply to every individual feedbacks.

Reader Comments
Max. 300 Characters

By clicking Submit you are agreeing to the Terms of Use.
*Offensive, insulting or inappropriate use of forum may lead to ban/restriction.
To avoid griefing, you will not be able to post or report for the first %d hours upon visiting this forum for the first time.


Looks like nobody posted here yet...

GameWith Announcements
Article Menu
Latest News
Mission Walkthrough
Walkthrough Guides
Infinite Ammo Weapons
Game Database
All Key Items
How To Get Guide
Beginner Tips
Useful Information
Resident Evil Resistance
All Characters
Other Resident Evil Guides