Sanctuary - Story Mission Walkthrough | Borderlands 3

Last Updated: August 21, 2022 10:32 PM

Read this Borderlands 3 story mission walkthrough guide of Sanctuary. Including mission tips, boss fight battles, and more!!!

Story Progression & Walkthrough

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Taking Flight	Hostile Takeover

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Sanctuary Walkthrough

Sanctuary Walkthrough Map

Sanctuary Walkthrough Chart

No.	Procedure
1	Head up to the ship to take flight
2	After the cutscenes, talk to Lilith to install the astronav
3	Watch the scenes unfold and then check on the different passengers to see if they're alright
4	Find Trannis and melee attack the button to get her out of the alien corpse
5	Locate the crew quarters and pull the lever to release them
6	Make your way to Marcus & shoot water pipes to put out fire
7	Talk to Marcus to purchase a Backpack SDU
8	Find Ellie and pull the lever to open the garage to space
9	Head down to Crazy Earl to get an entropy accelerator
10	Find Moxxi's nightclub to get Eridium from her slot machine
11	Take the Eridium and get the entropy accelerator from Crazy Earl
12	Head back up and place the entropy accelerator into the ship's slot
13	Go to the bridge & navigate to Promethea to end the mission

1-13. Basic Fetch & Deliver Quest

In this part of the game, you only need to talk to NPCs and fetch items that they need. There is no combat involved and only requires you to do basic moving around.

4. Melee Attack Button To Release Trannis

The button you need to press to release Trannis is to the left of the alien corpse, when you've just entered the room. You need to use your melee attack button to rescue Trannis.

6. Shoot Water Pipes To Douse Fire

When you help Marcus out, he will ask you to douse the flames engulfing his part of the ship. Shoot the water pipes to put down the fire surrounding the area.