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Mission 2 - Story Mission Walkthrough

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Mission 2 - Story Mission Walkthrough

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Check out this Devil May Cry 5 (DMC 5) main story walkthrough and guide for Mission 2 - Qliphoth. This includes gameplay & battle tips, mission tricks & techniques, and more.

Mission 2 - Story Mission Walkthrough

Mission Progression & Walkthrough

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Mission 1Mission 3
All Mission Guide & Walkthrough List

Table of Contents

Mission 2 - Walkthrough

Mission 2 - Walkthrough Chart

1From the starting point, head straight till you get to the area with petrified humans
2Follow the creature at the back end of the area to trigger a cutscene
3Defeat the Empusas that appear
4Continue past the wall, and vault over it
5Head to the area with the Pegasus statue
6Defeat the Hell Cainas
7Enter the Chiaro Mondo Hotel
8Clear the Empusa that spawn in the hotel and courtyard
9Head up the Hotel and enter through the door on the right
10Circle around the room to get to the door blocked by tentacles
11After the cutscene, immediately head left and use the Nidhogg Hatchling on the obstacle
12Pass through the new doorway, and head left to enter a building
13Go up the stairs, and enter the room in the hall on the right side
14Defeat the Hell Cainas that spawn
15Continue along the path, and use a Nidhogg Hatchling to unblock your way
16A tentacle will block your way, so head to the room to your right
17Pass through the room's door, and enter the first doorway on your left
18Defeat the Hell Cainas in the room
19Go out of the room, and jump down from the balcony
20Head to the right side of the Crossroads, and get the Nidhogg Hatchling
21Head back to the blocked area to trigger a cutscene
22Defeat the Hell Antenoras that spawn
23Use the Nidhogg Hatchling on the blocked area
24Continue down the path, and head to the phone booth to call Nico
25After customizing, head up the path, behind the van to trigger a cutscene
26Defeat Goliath to trigger a cutscene

Mission 2 Tips & Tricks

3, 8. Defeating Empusa - Tips

Focus On One Enemy At A Time

Focus On One Enemy At A Time

Empusas are not very fast enemies. You can easily handle them by focusing on one enemy at a time. When you see more enemies getting too close, relocate further away, and pull one closer to you.

3. Find Gold Orb To Right Of Defeating Empusas

Devil May Cry 5 Gold Orb Location Mission 2

After the battle, you can find a Gold Orb by double jumping over the raised piece of road to the right of the area where you first fought the Empusas. The Gold Orb is at the dead end of the area.

Check Out All Gold Orb Locations Here!

3. Take Right Path To Find "Where Red Orbs Grow" Achievement

Devil May Cry 5 Where Red Orbs Grow Achievement Location

After defeating the Empusas and moving forward, the path will split into two. Take the right path & jump up the ledge. Go into the hole in the wall and into a small room. Break the red orbs growing on trees here to get the trophy "Where The Red Orbs Grow".

6, 14, 18. Defeating Hell Cainas - Tips

Easy To Dodge Attacks Cause Of Slow Wind Up

Easy To Dodge Attacks Cause Of Slow Wind Up

Hell Cainas have a slow wind up, which makes them easy to dodge. You can read them telegraphing their attacks when they start to lift their scythes behind them. When they do this, dodge out of the way to avoid getting hit.

14. After Defeating Hell Cainas - Tips

Collect Blue Orb Fragment

Blue Orb Mission 2

At a room where Nidhogg is located, the floor will break down while combat, and create a hole. This floor holds a Blue Orb Fragment that you can get.

Check Out How To Collect Blue Orb Fragments

16. In The Room To Your Right - Tips

Secret Mission Available

Secret Mission Available

The wall around the doorway will have a symbol drawn onto it. Align it correctly to unlock and complete the Secret Mission 01.

20. Before Getting The Nidhogg Hatchling - Tips

Collect Blue Orb Fragment

Collect Blue Orb Fragment

Before making a left to the Nidhogg Hatchling, you will find a Devil Breaker on the right side of the path. Jump up onto the platform, and into an opening on the building to find a Blue Orb Fragment waiting for you.

Check Out How To Collect Blue Orb Fragments

22. Defeating Hell Antenoras - Tips

Slow, But Long Attacks

Slow But Long Attacks

Hell Antenoras are generally slow, but they have a string of attacks. Do not get close to them until they finish their attacks so as to avoid getting hit.

24. Calling Nico - Tips

Customize As Soon As She Appears

Customize As Soon As She Appears

Once Nico appears, you will have the chance to customize your loadout. Make sure that you do since this is your last chance to stock up on equipment before fighting Goliath.

Goliath Boss Tips & Strategy

Check Out Goliath Boss Fight Guide Here!

Telegraphs His Attacks

Telegraphs His Attacks

Goliath's attacks are pretty easy to dodge due to their slow wind up. When he starts his attack animation, stop your combo, dodge out of the way.

Steer Clear Of His Fire Vacuum Attack

Steer Clear Of His Vacuum Attack

Goliath will also attack with fire from his belly that will suck in anything in its path. It is best to run away from the Fire Vacuum's direction, and Break Away when you are caught.

Collect Green Orbs When Low On Health

Collect Green Orbs When Low On Health

When you are low on health, it is best to keep an eye out for Green Orbs in the area to restore some of your health. It is best only to collect these, when your health is dangerously low.

Use Guns To Chip Away At His Health

Use Guns To Chip Away At Hit Health

There are times when Goliath will not let you near him because of his attacks. If you are far away, you can use your guns to chip away at his health.

Charge Up Devil Breakers To Deal Massive Damage

Charge Up Devil Breakers To Deal Massive Damage

You can charge up your Devil Breakers to deal a ton of damage to the Goliath. It is best to use the Gerbera since it can shoot a laser beam from far away.

Mission Progression & Walkthrough

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Mission 1Mission 3
All Mission Guide & Walkthrough List

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