Resident Evil 2 Remake
Resident Evil 2 Remake: Walkthrough & Strategy Guide
Leon A Walkthrough Pt.6: Laboratory ~ Ending
Resident Evil 2 Remake | Leon A Walkthrough Pt.6: Laboratory ~ Ending | RE2

Resident Evil 2 Remake | RE2
Leon A Walkthrough Pt.6: Laboratory ~ Ending

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Check out this guide for the full Leon story walkthrough of the Resident Evil 2 Remake from the NEST Laboratory until the Game Ending, including gameplay tips, guides, and more!

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

Story Progression & Walkthrough

<< Previous PartCurrent PartNext Part >>
Sewers ~
vs. G (2nd Form)
Laboratory ~
Ending
[B] Opening ~
RPD
Check Out All Story Walkthrough Here!

Table of Contents

Laboratory ~ Plant 43

Laboratory ~ Plant 43 Walkthrough Chart

No.Procedure
1 After rescuing Ada, follow her into a cable car to head into the laboratory
2 After the cutscene, you'll receive an ID wristband - then head through the door on the right to the cafeteria
3 Find the ladder inside the cafeteria, climb it and get into the ducts to reach the kitchen
4 Move through the kitchen to the left of the map and into the Nap Room. Additional tips below.
5 Check the corpse inside the Nap Room an Electronic Chip that upgrades the security access of your bracelet to General Staff
6Acquire the Regulator (Flamethrower) at the Nap Room. Additional tips below.
7 With more security access, open the blue door and go through another door next to the guard room
8 In the Main Shaft, use your ID wristband to create a bridge to the center of the area
9 Use the ID wristband to create a bridge to the East Area then move through the lobby and conference room to get to the Greenhouse Control Room
10 In the control room, activate the glowing machine to trigger a cutscene and receive the Dispersal Cartridge
11 Go to the south-eastern corner of the Greenhouse to get the cryptographic code - input the code in the greenhouse control center. Additional tips below.
12 Return to where you got the code and go down the ladder
13 Move down the corridor and examine the object in the lounge to find another code. Additional tips below.
14 Return to the control room and enter the 2nd code
15 Go to the Drug Testing Lab to fill up the Dispersal Cartridge with Solution
16 Go upstairs to retrieve the signal modulator - go down and find the switchboard & match with the frequency titled "MURF" Additional tips below.
17 Move to the Low-Temp Testing Lab room and use the machine to cool down the Dispersal Cartridge to hold Herbicide
18 Return to the control room and use the Dispersal Cartridge to dispense the solution

4. Kitchen - Hint & Tips

Zombies Are Behind Kitchen Door

Zombies will be behind the kitchen door when you open it so be careful. Step aside & quickly run through them to avoid drawing in more attention with gunshots.

6. Acquire the Regulator (Flamethrower) at the Nap Room

The Regulator Custom Part can be found in one of the lockers in the Nap Room. Make sure to take this before you leave.

Map View

Resident Evil 2 Flamethrower Regulator Custom Part

Close Up

Resident Evil 2 Flamethrower Regulator Custom Part

11. Go to the south-eastern corner of the Greenhouse to get the code

Code Solution

Resident Evil 2 1st Laboratory Code Solution

13. Find The Code - Hint & Tips

Code Is Written When Examining Object

Resident Evil 2 Flamethrower 2nd Code Laboratory

You can find the code for the greenhouse control center by examining the object you find in the lounge. The code will be written on it.

16. Signal Modulator - Hint & Tips

Use Dials To Adjust Wavelength

You need to match the wavelength of the signal modulator. You can adjust the width of the waves using the left dial and the vertical height of the waves via the right dial.

Map View

Resident Evil 2 Signal Modulator

Close Up

Resident Evil 2 Signal Modulator

Laboratory ~ Vs. G (3rd Form)

Laboratory ~ Vs. G (3rd Form) Walkthrough Chart

No.Procedure
1 Search the corpse in the Greenhouse to find an Electronic Chip to upgrade your ID wristband- The Tyrant will appear here. Additional tips below.
2 Leave the Tyrant alone, go back to the Main Shaft
3 Go to the North Area to retrieve a Hip Pouch. Additional tips below.
4 Go back to the Main Shaft and use your ID wristband to get access to the West Area. Additional tips below.
5 Cross the bridge and search through corpses to retrieve Lab Digital Video Cassette
6 Find the switchboard and match the signal modulator frequency with the one titled "OSS"
7 Go to the nearby VCR and play the Lab Digital Video Cassette
8 Move to the biological laboratory, through the biological cultural tank and then to the P-4 level lab to retrieve the G-virus
9 Go back to Ada to encounter G (3rd Form) in the Bioreactors Room
10 Defeat G (3rd Form)
11 Once you defeat G, meet up with Ada to trigger a cutscene

1. Find Electronic Chip - Hint & Tips

Electronic Chip Is On Scientist Corpse In Greenhouse

Go around the Greenhouse and find the corpse with a white lab coat. This corpse has an Electronic Chip that will upgrade your ID wristband to Senior Staff.

Map View

Resident Evil 2 Electronic Chip

Close Up

Resident Evil 2 Electronic Chip

3. Go to the North Area to retrieve a Hip Pouch

Go back to the Nap Room and use the Signal Modulator here to retrieve the Hip Pouch hidden in one of the sleeping pods. Match the frequency for MUF.

Map View

Resident Evil 2 MUF Hip Pouch

Close Up

Resident Evil 2 MUF Hip Pouch

6. Signal Modulator - Hint & Tips

Use Dials To Adjust Wavelength

You need to match the wavelength of the signal modulator. You can adjust the width of the waves using the left dial and the vertical height of the waves via the right dial.

Battle Strategy Vs. G (3rd Form)

Focus Fire On G's Giant Eyes

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

G will have several giant eyes around its body. Focus fire on them to deal big damage to G. If you deal enough damage, the eyes will close - this is the goal.

When Down, Aim For Cluster Of Eyeballs On G's Chest

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

When you've closed all eyeballs on G's body, he'll drop down, turn over, and expose a cluster of eyeballs on his chest. Aim for this cluster to bring down his health & inflict damage.

Concentrate Shots On Eyeballs On Chest

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

If you keep hitting G's eyeballs & making him drop down, you'll eventually expose the eyeballs on his chest. Concentrate your shots on this part of G's body to take him down.

Stay Back & Keep Distance From G's Swing Move

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

G will have a large swing attack done with both his arms. Keep your distance to avoid getting hit or damaged by G.

Escape ~ Vs. The Tyrant

Escape ~ Vs. The Tyrant Walkthrough Chart

No.Procedure
1 Take the central elevator down from the center of the Main Shaft - the 10 min. countdown will begin
2 Move forward from the monitoring room to find an item box & typewriter then head into the pump room
3 Move forward through the duct and a cutscene will trigger where The Tyrant will appear
4 After the cutscene, you'll be in a different location and you'll have a Joint Plug in your inventory
5 Insert the Joint Plug into a nearby panel to initiate the fight with The Tyrant
6 Defeat Super Tyrant
7 After defeating The Tyrant, move forward down the road to start another cutscene which leads to the game ending

4. Joint Plug - Hints & Tips

Placing Joint Plug Triggers Tyrant Fight

Be careful about placing the Joint Plug into the panel as this will immediately start the final fight with The Tyrant. Only initiate the battle when you're ready and full-equipped with bullets & recovery items.

Battle Strategy Vs. The Tyrant

Take The Tyrant Down With Well-Placed Shots

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

The only way to take down The Tyrant is by sheer firepower. It's best to keep your distance and make well-placed shots that deal maximum damage instead of getting trigger-happy. The Tyrant has high defense so it can easily withstand shots and land counterattacks.

Stay Cautious Of His One-Shot Kill Attack

Once you damage The Tyrant enough, he'll attack you with a super strong move. If you get hit with your HP reduced, you'll die instantly so it's better to dodge. Leon will warn you with "Uh oh... Not good" when he is about to make this move.

Battle Ends With the Rocket Launcher

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

If you've done enough damage to The Tyrant, a cutscene will trigger and you'll get a rocket launcher. Pick it up and use it to finally defeat The Tyrant.

Check Out How to Get the Anti-Tank Rocket

Story Progression & Walkthrough

<< Previous PartCurrent PartNext Part >>
Sewers ~
vs. G (2nd Form)
Laboratory ~
Ending
[B] Opening ~
RPD
Check Out All Story Walkthrough Here!

Resident Evil 2 (RE2) Related Article

Story Mission Walkthrough

Game Mode

Check Out How to Unlock Infinite Ammo Weapons

Game Database

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Part 1: Opening ~ Underground Facility Part 2: Underground ~ Vs. G 2nd Form Part 3: Laboratory ~ Ending
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