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Resident Evil 2 Remake: Walkthrough & Strategy Guide
Leon B Walkthrough Pt.6: Laboratory ~ Ending

Resident Evil 2 Remake | RE2
Leon B Walkthrough Pt.6: Laboratory ~ Ending

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Check out this guide for the full Leon Side B story walkthrough of the Resident Evil 2 Remake from the NEST Laboratory until the Game Ending, including gameplay tips, guides, and more!

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

Story Progression & Walkthrough

<< Previous PartCurrent PartNext Part >>
[B] Sewers ~
vs. G (2nd Form)
[B] Laboratory ~
Ending
-
Check Out All Story Walkthrough Here!

Table of Contents

Laboratory ~ Plant 43

Laboratory ~ Plant 43 Walkthrough Chart

No.Procedure
1Get inside the cable car with Ada. This will trigger a cutscene where you'll get the ID Wristband
2Head inside the door on the right to the cafeteria
3Climb up the ladder in the cafeteria. Use the duct to get the kitchen
4Head to you left to get into the Nap Room. Additional tips below.
5In the Nap Room, get the electronic chip from the corpse there. The Electronic Chip will upgrade your placement to access the General Staff
6Take the Regulator (Flamethrower) from the Nap Room. Additional tips below.
7Go inside the blue door and go through another door next to get to the Security Room to get the map
8Head to the Main Shaft, use your ID wristband to call a bridge to the center of the area to the East Area
9Get the signal modulator in the north side of the Main Shaft. Additional tips below.
10Pass through the lobby and conference room to get to the Greenhouse Control Room
11Activate the machine there. This will trigger a cutscene where you will obtain the Dispersal Cartridge
12Head to the southeastern corner of the Greenhouse to get the 1st cryptographic code. Input this to the Greenhouse Control Center. Additional tips below.
13Go back to the panel where you found the first the code. Solve the Signal Modulator puzzle there to open the electricity
14Head down the corridor and examine the trophy in the lounge to find the 2nd code. Additional tips below.
15Return to the control room and enter the 2nd code
16Move to the Drug Testing Lab and fill up the Dispersal Cartridge with the right amount of solution
17Get to Low-Temp Testing Lab room. Cool down the Dispersal Cartridge with the machine there so it can hold Herbicide
18Return to the control room. Dispense the solution with the Dispersal Cartridge

4. Head to you left to get into the Nap Room

Zombies Are Behind Kitchen Door

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

Be careful when first going into the Kitchen as there are zombies hiding behind the Kitchen door. Once you open, it's best to just lead them away from the door and zip past through to conserve ammo.

6. Take the Regulator (Flamethrower) from the Nap Room

Regulator (Flamethrower) Location

Resident Evil 2 Flamethrower Regulator Custom Part

the Regulator (Flamethrower) mod can be found in the Nap Room. You'll have to go past the Kitchen first to get inside the room.

Regulator (Flamethrower) is Inside the Locker

Resident Evil 2 Flamethrower Regulator Custom Part

Don't leave the nap room without getting the Regulator (Flamethrower) first. You can find it in a locker inside the room.

9. Get the Signal Modulator

Use Dials To Adjust Wavelength

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

You need to match the wavelength of the signal modulator. You can adjust the width of the waves using the left dial and the vertical height of the waves via the right dial.

12. Head to the southeastern corner of the Greenhouse

The Code is on a Sticker on the Ladder

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

You will find the code inside the southeastern corner of the Greenhouse. It's a sticker stuck on the ladder.

14. Find The 2nd Code - Hint & Tips

Code is Under the Trophy

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

The 2nd code can be found under the trophy you find in the lounge. Examine the object in your inventory to see what is underneath it.

Laboratory ~ Vs. G (3rd Form)

Laboratory ~ Vs. G (3rd Form) Walkthrough Chart

No.Procedure
1Search the corpse in the Greenhouse to find the 2nd Electronic Chip to upgrade your ID wristband. This will cause the Tyrant to appear. Additional tips below.
2Head back to the Main Shaft and use your ID wristband to get access to the West Area
3Cross the bridge and search through corpses in the West Area. Take the Lab Digital Video Cassette
4Find the switchboard in the West Area north of the Biotesting Lab and match the Signal Modulator frequency. Additional tips below.
5Use the VCR inside the room and play the Lab Digital Video Cassette
6Go through the Biological Testing Room and the Biological Cultural Tank. Head to the P-4 level lab to retrieve the G-virus
7Head back to the Bioreactors Room to Ada. The G (3rd Form) will appear here
8 Defeat G (3rd Form). Additional tips below.
9Meet up with Ada. This will trigger the cutscene

1. Find Electronic Chip in the Greenhouse

Electronic Chip Location

Resident Evil 2 Electronic Chip

The Electronic Chip is in a corpse inside the Greenhouse. You can identify the corpse with its white lab coat.

Electronic Chip Is On Scientist Corpse In Greenhouse

Resident Evil 2 Electronic Chip
:p The corpse with a white lab coat inside the Greenhouse has the Electronic Chip. Take it from him to be able to upgrade your ID wristband.

4. Match the Signal Modulator Frequency

Use Dials To Adjust Wavelength

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

You need to match the wavelength of the signal modulator. You can adjust the width of the waves using the left dial and the vertical height of the waves via the right dial.

8. Defeat the G (3rd Form)

Aim for the G (3rd Form)'s Eyes

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

The G (3rd Form)'s weaknesses are the giant eyes around its body. Focus on these eyes to do as much damage as you can. Once all the eyes are close, the G (3rd Form) will drop down.

Aim For Cluster Of Eyeballs On G's Chest

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

When you've closed all eyeballs on G's body, he'll drop down, turn over, and expose a cluster of eyeballs on his chest. Shoot the eyeballs there to inflict the most amount of damage.

Keep Distance From G

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

The G (3rd Form) has a large swing attack done with both his arms. Keep out of range of the swing by keeping your distance from the G (3rd Form).

Escape ~ Vs. The Tyrant

Escape ~ Vs. The Tyrant Walkthrough Chart

No.Procedure
1Go down using the central elevator in the the Main Shaft. Doing so will cause the 10 min. countdown to begin
2 Move forward to monitoring room. Look for the item box then head into the pump room
3Go through the duct and a cutscene will trigger. The Tyrant will appear here
4After the cutscene, you'll be in a different location. You will also have a Joint Plug in your inventory
5Initiate the fight with the Tyrant by inserting the Joint Plug. Additional tips below.
6Defeat Super Tyrant. Additional tips below.
7Move forward to the train station
8Head to the back of the train. This will trigger the final fight against the G
9Defeat the G (5th Form). Additional tips below.

5. Initiate the Fight by Inserting the Joint Plug

Tyrant Fight will Initiate Immediately

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

Once the Joint Plug is inserted, the fight against the Tyrant will immediately start. Be sure you're ready for the battle before doing so as there's no going back after this.

6. Defeat the Tyrant

Take The Tyrant Down With Well-Placed Shots

Resident Evil 2 Leon Story Walkthrough Pt.6: Laboratory ~ Game Ending

Make your shots count. The Tyrant can tanks a lot of damage and with no ammo to be looted, you'll have to be extra careful when using your bullets.

Be Careful of his One-Shot Attack

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

The Tyrant has a One-Shot Attack that will immediately kill you if you get hit by it. Once you he starts screaming, make precautions to dodge his attack.

Use the Rocket Launcher to Finish the Tyrant

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

Once you've dealt a certain damage to the Tyrant, a cutscene will happen. After it ends. the Rocket Launcher will be on the floor. Loot it and shoot down the Tyrant.

Check Out How to Get the Anti-Tank Rocket

9. Defeat the G (5th Form)

Continue Damaging the G (5th Form) to Open Its Eye

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

The G (5th Form) won't open its eye on its own. Continuously deal damage to it until you get to the point where it needs to open its eye.

Use Rocket Launcher to Shoot G (5th Form)'s Eye

Resident Evil 2 | RE2 Leon B Walkthrough Pt.6: Laboratory ~ Ending

Make use of your remaining Rocket Launcher shots to deal tons of damage to the G (5th Form). Aim for the eye to further multiply that damage as that is its weak point.

Story Progression & Walkthrough

<< Previous PartCurrent PartNext Part >>
[B] Sewers ~
vs. G (2nd Form)
[B] Laboratory ~
Ending
-
Check Out All Story Walkthrough Here!

Resident Evil 2 (RE2) Related Article

Story Mission Walkthrough

Game Mode

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Game Database

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