RE5
Resident Evil 5 - Walkthrough & Strategy Guide
Chapter 5-3 - Wesker & Jill Boss Fight
Resident Evil 5 | Chapter 5-3 - Wesker & Jill Boss Fight | RE5

Resident Evil 5 | RE5
Chapter 5-3 - Wesker & Jill Boss Fight

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Read this Chapter 5-3 walkthrough guide of Resident Evil 5 (RE5), including Wesker & Jill boss fight tips, emblem locations and more.

Table of Contents

Story Progression Chart

Previous PartNext Part
Chapter 5-2Chapter 6-1
Check Out Main Mission Walkthroughs Here!

Chapter 5-3 Walkthrough

Uroboros Research Facility Mission Walkthrough

No.Procedure
1Climb up the ladder found at the room attached to the large laboratory area
2Head left to a room with X-Ray scans. Loot for ammo
3Exit the room then continue down the hallway & up the stairs
4Open the door at the end of the hallway
5Move forward through the halls. Enter the door next to a grate
6Follow the path of the metal walkway
7Continue down the path to a yellow door. Use the Generator to activate the lever
8Pull the lever to operate the platform
9Continue down the path to the left
10Enter the room with a yellow door
11Exit through the white door. Continue forward then open the next door
12Continue down the metal walkway
13Use the lever on the console to move the platform
14Defeat the enemies on the platforms
15Defeat the 2nd wave of enemies
16Head up the stairs. Open the door at the end of the hallway
17Use the generator found near the bridge
18Call for the lift and head up to the upper scaffolding
19Follow the scaffolding. Push the cart that blocks the way
20Drop down to the building. Use the controls to lower the bridge
21Open the door at the end of the bridge
22Defeat Wesker & Jill

Chapter 5-3 Mission Tips

6. ~ 7. Walk Across the Metal Walkway

Reaper Insect Monsters Spawn from Sacs

Reaper Insect Monsters Spawn from Sacs

As you move across the walkway, you will come across sacs hanging from the ceiling. These sacs will spawn a Reaper when you get too close. Attack its bulbous spots for more damage.

7. Enter the Yellow Door & Activate the Generator

Loot the H&K PSG-1 in the Room

Loot the H&K PSG-1 in the Room

Besides the Generator, there are numerous crates that you can break and a silver weapon box inside the room. Open the weapon box to get the H&K PSG-1 Rifle!

8. Pull the Level to Operate the Platform

h4:Shoot Enemies Riding the Platform to You
Shoot Enemies Riding the Platform to You

While they're at the platform, the enemies won't be able to attack you. Take advantage of this! Keep shooting them so they never make it to your side.

9. Continue Down the Path to the Left

Stay Behind Cover to Escape Rockets

Stay Behind Cover to Escape Rockets

Multiple enemies with rocket launchers will be in this area. Use the cover provided by the walkway to saty safe. Peek and shoot at them whenever they're reloading.

10. Enter the Room with a Yellow Door

Enemies Waiting Inside

Enemies Waiting Inside

Don't just stroll inside the operator room as there are multiple enemies waiting inside with one equipped with a Rocket Launcher. Shoot at them from the open window to the side of the room before going in.

14. ~ 15. Defeat Waves of Enemies

Platform will Continue to Rotate

Platform will Continue to Rotate

The Platform will continuously rotate as it goes up the tower. Aiming will be harder due to this. It's better to use weapons with less recoil for this part.

Shoot Enemies Holding on to Levers

Shoot Enemies Holding on to Levers

To continue you ascent up the tower, you'll need to take care of the enemy holding down the lever on their hand. Shoot them as soon as you find their location.

Wesker & Jill - Boss Fight Tips

Wesker Boss Fight Guide

Need to Survive Against Wesker for 7 Minutes

Need to Survive Against Wesker for 7 Minutes

You don't need to shoot down Wesker in this battle. As long as you make it to the 7 minute mark, Wesker will go away on his own.

Use Hallways to Kite Around Wesker

Use Hallways to Kite Around Wesker

Head inside the hallways to get out of Wesker's line of sight. So long as he doesn't see you, he will just slowly walk around the area.

Jill Boss Fight Guide

Do Not Shoot at Jill

Do Not Shoot at Jill

If Jill dies, the mission will fail. Your objective is to remove the contraption on her chest. Shooting at her will lead to nothing, but her death and the mission's failure.

Stay in her Melee Rage

Stay in her Melee Rage

You'll need to stay close to Jill throughout this fight. Either Chris or Sheva can hold on Jill or tear off the device on her chest.

Must Be Done Multiple Times

Must Be Done Multiple Times

You won't get the device out immediately. It will take at least 3 tries before it will completely come off Jill. Make sure to do the button prompts to do so.

Chapter 5-3 Emblem Locations

Chapter 5-3 Emblem 1 - Behind Giant Fan

Chapter 5-3 Emblem 1 - Behind Giant Fan

Before exiting the Uroboros boss fight area, check behind the giant metal fans. The fan on the right has the emblem behind it.

Chapter 5-3 Emblem 2 - On Lever Platform

Chapter 5-3 Emblem 2 - On Lever Platform

This emblem can be found on the platform where enemies pull levers to bring down the spinning platform. It's best to wait for the platform to fully stop or to slow down before attempting to shoot this emblem.

Chapter 5-3 Emblem 3 - On Elevator Shaft

Chapter 5-3 Emblem 3 - On Elevator Shaft

When you reach the area where the ruins begin again, before turning on the elevator, check the shaft. The emblem is on the same side as its lever, so move to the opposite side to spot it.

Check Out All BSAA Emblem Locations!

Story Progression Chart

Previous PartNext Part
Chapter 5-2Chapter 6-1
Check Out Main Mission Walkthroughs Here!

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