Read this Spider-Man PS4 guide for more information about Act 3 Main Mission Story- walkthroughs, tips and tricks, & more!

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Check Out Main Mission Guide & Tips!Table of Contents
Act 3 - 1: ...Into the Fire
No. | Procedure |
---|---|
1 | Go to the top of the Empire State Building |
2 | Head to the Upper East Side |
3 | Survive against Inner Demons and destroy the 5 transformers |
4 | Defeat the Inner Demons on the ground |
5 | Head to the Upper West Side |
6 | Help the police defend against the convicts |
7 | Defeat the convicts in the first, east, & south barricades |
8 | o up to the rooftops and take care of the rocket launcher-wielding enemies |
9 | Deal with the Sable troops |
10 | Head to the Veteran's Center |
8. 9. 10. Throw Enemies Off Buildings for Faster Battles

Use moves like Swing Kick, Web Throw, and gadgets to quickly take out enemies by throwing them off buildings! Enemies thrown off buildings will be quickly incapacitated, giving you time to focus on tougher enemies.
Check Out Combat Tips HereUse Moves that Can Hit Multiple Enemies

With so many enemies, you can easily be ganged up on. Make sure to have a move that can hit multiple enemies at once to give you breathing space during fights!
Check Out The Suit Powers HereAct 3 - 2: Picking Up the Trail
No. | Procedure |
---|---|
1 | Head to Times Square and talk to the policeman |
2 | Inspect the back of rally signs in Times Square |
3 | Complete the Spectrograph puzzle |
4 | Inspect the area for a dispersal path |
5 | Follow any of the trails that goes up the building |
6 | Search for the access vent near the Crow's Nest billboard |
7 | Shoot the electric box to open the lights |
8 | Read through all the clues about the Sinister Six |
9 | Inspect the UV bulb and turn on the switch |
10 | Search for an electric box and hit it with the Electric Web |
11 | Read through the map, make sure to inspect all the circled parts |
12 | Check out the safety box on top of the ICARUS crate |
13 | Boss Fight Phase 1: Attack Electro and destroy his Conductor |
14 | Boss Fight Phase 2: Defeat Vulture |
15 | Boss Fight Phase 3: Defeat both Vulture and Electro |
2. Follow the Pattern to Complete the Spectograph Puzzle

Layer the lines above and below to create thicker lines to match the pattern.
Battle Against Electro & Vulture

Dodge electric attacks & feather blades in this aerial-focused battle against Electo & Vulture. Take note of the on-screen prompts and destroy the conductors to defeat the first two members of Sinister Six.
Check Out the Electro & Vulture Boss Fight Guide15. Incapacitate Electro & Vulture to Get an Opening

Electro and Vulture are invulnerable to attacks unless you web then up first or get prompted to do so in the case of Vulture. Once you web them, use △ to zip them and start combo attacks.
Use Takedowns on Electro & Vulture

Takedowns will not immediately finish them off when you use them, but they do a lot of damage! Use them whenever you see the prompts.
15. Take Out Electro First to Make the Fight Easier

Electro's attacks hits harder and are more erratic than Vulture so focus on taking him out first. You can easily escape and counter Vulture's attacks while focusing aggro on Electro.
Act 3 - 3: Streets of Poison
No. | Procedure |
---|---|
1 | Head to Central Park |
2 | Escape the pool of poison by heading towards the marked location |
3 | Analyze the poison and complete the Spectrograph puzzle |
4 | Head to the ESU greenhouse to get the first ingredient for the antidote |
5 | Move forward and zip across your hallucination to get the ingredient |
6 | Head to research station in Midtown |
7 | Move across your hallucination and grab the ingredient |
8 | Go to Dr. Octavius' Lab in Greenwich |
9 | Move through your hallucination |
10 | Defeat the Scorpion hallucinations |
11 | Use the computer to cure yourself |
3.Follow the Pattern to Complete the Spectrograph Puzzle

You will need to subtract lines and layer the fragments to be able to complete this puzzle. Put the fragment with 3 lines on the top left and the fragment with four lines at the top right.
2. 4. 6. 8. Swing High to Stay Out of the Poison Pool

Use web zips to cover more ground without losing altitude as you traverse through the poison-flooded streets of New York. It's good to always check if you have buildings to attach to as you move.
Check Out Tips to Move Faster Here6. 8. Dodge the Large Scorpion Tails as You Traverse

Scorpion Tails will come out from the poison pools to strike as you find the 2nd and 3rd ingredients. Take cue from your Spider Sense to dodge them before they could hit you.
10. Scorpion Hallucinations Go Down Quickly

With just a few hits, you can easily bring down a Scorpion Hallucination. Focus more on dodging and looking for openings to web them up before going on the offensive.
Act 3 - 4: Supply Run
No. | Procedure |
---|---|
1 | As Spider-Man, Head to F.E.A.S.T. |
2 | Help Aunt May |
3 | You will switch over to Miles for this section |
4 | Move to the right to avoid the enemies standing guard |
5 | Hack the the floodlight and move forward |
6 | Go through the middle of the flipped cars |
7 | Inspect the medicine then move to your right |
8 | Hack either the drone or the fire alarm and move to its opposite end |
9 | Follow the marker across the base |
10 | Hack either the item on the guard's left or right then move to the overturned car |
11 | Hack the floodlight to distract Rhino then head to the drain entrance |
12 | Get to the end of the drainage then move to the other side |
13 | Stay behind green containers and wait until he's on the other side before running past him |
14 | Move to the left of the the forklift then up the containers |
15 | Walk across the containers then go into a drain tunnel to hide |
16 | Stay close to the yellow wall and go inside the yellow container |
17 | Hack the generator then run when Rhino goes to the other side |
Avoid Broken Glass to Remain Hidden

Don't step on broken glass to stay hidden. Walking on the glass will create noise that might alert enemies to your location.
Time Your Movements Between Cover

Make sure that you are out of the line of sight of the guards before moving between cover. If they find you, it's game over and you will have to redo the section again.
Act 3 - 5: Heavy Hitter
No. | Procedure |
---|---|
1 | Head to the shipping yard in Harlem |
2 | Boss Fight Phase 1: Damage Rhino |
3 | Boss Fight Phase 2: Defeat Rhino & Scorpion |
Dodge and Fight Against Rhino & Scorpion

You'll have to think fast as you get pressured by the charging presence of Rhino and the agile strikes of Scorpion in this boss fight. Throw objects at Rhino and web up Scorpion to win this fight.
Check Out the Scorpion & Rhino Boss Fight GuideFocus on Scorpion First in this Boss Fight

Scorpion can be an annoying obstacle in the fight so it's advised to take him out first. It takes little to eliminate him so focus damage first on Scorpion before dealing with Rhino.
2. Lead Rhino To Yellow Outlines On The Ground

Yellow outlines around the cargo indicate overhead objects you can use to bring down Rhino. Lead him to these areas and time when to pull down the objects to stagger him.
3. Use Web to Incapacitate Scorpion
Scorpion will use height to his advantage and you will need to bring him down to the ground. Web him up then press △ to Web Zip and start a combo!
Act 3 - 6: Step Into My Parlor
No. | Procedure |
---|---|
1 | As Spider-Man, head to Osborn's Penthouse |
2 | You will switch to Mary Jane for this section |
3 | Rile up the 3 resident groups as a distraction then sneak behind the guards |
4 | Take the Stun Gun then take out the Sable guard that comes out the door |
5 | Go to the next hall. Throw a lure behind the Sable guard then stun him when his back is turned |
6 | Head to the security room on your left. Take out the Sable guard there |
7 | Set the alarm before going back to the lobby |
8 | Sneak into the elevator Osborn used to get to his penthouse |
9 | Inspect the Penthouse blueprints on the small table at the study |
10 | Go to the study and inspect the helmet and blueprint on Osborn's desk |
11 | Use the mask to examine the wall next to Harry & Norman's portrait |
12 | Move the portrait to see the the keypad |
13 | Go to the kitchen and read the note on the dining table |
14 | Inspect the portrait of Osborn's wife in his bedroom |
15 | Go into Harry's room then read his diary |
16 | Leave the room and stay behind cover. Move to the left side of the living room as the Sable guard moves forward |
17 | Hide behind the table with the phone. Throw a lure behind the Sable guard and stun him once his back is turned |
18 | Go to the kitchen then turn left to the lounge area |
19 | Move quickly and remain hidden from the 3 Sable guards. Head to the hidden room |
20 | Inspect the contents of the hidden room |
21 | Activate the 3D map. Highlight Dr. Michaels, Oscorp Record Buildings, & Sable's Bravo Patrol |
22 | Inspect the building where the they all overlap |
23 | Stay behind cover and move your way to the dining table |
24 | Follow the Sable Guard to the outdoor pool stun him then go through the bathroom |
25 | Throw a lure to the guard to the bedroom then head to the balcony |
26 | Take out the Sable Guard in the balcony |
Unlock the Stun Gun for Mary Jane in this Mission

MJ will be able to perform takedowns with the Stun Gun, but only if the target is unaware of her position. Sneak behind enemies to take them down!
Time Your Movements Between Cover

Make sure that you are out of the line of sight of the guards before moving between cover. If they find you, it's game over and you will have to redo the section again.
Act 3 - 7: The Heart of the Matter
No. | Procedure |
---|---|
1 | Head to the Oscorp's Record Building |
2 | Take out the Inner Demon snipers and guard on the rooftops |
3 | Defeat the Inner Demons on the ground |
4 | Take out the Sable reinforcements |
5 | Go inside the Records Building |
6 | Head to the elevator shaft then go to the ground floor |
7 | Go down the hole until you get to where Mr. Negative is |
8 | Follow the Mr. Negative's phantoms |
9 | Boss Fight Phase 1: Damage Mr. Negative |
10 | Boss Fight Phase 2: Defeat Mr. Negative |
Fight Against Mr. Negative in Your Final Confrontation

After two battles, you'll finally face Mr. Negative for the last time in the negative space. Fight your way against his henchmen and a large negative energy oni to finally take him down.
Check Out the Mr. Negative (Pt 2) Boss Fight Guide9. Throw Objects at Mr. Negative to Create an Opening

Mr. Negative's sword attack packs quite a punch so throw an object at him to stagger him then use △ to zip up to him and start a melee combo. Time when you jump back to escape his attack!
10. Take Out the Henchmen First

Mr. Negative will summon henchmen during your fight with him. Take a few of them out first before focusing on Mr. Negative as they give you focus and it'll clear up the battlefield!
10. Jump To Avoid Demon's Arm Swipe Attack

Mr. Negative's demon will appear a couple of times in the fight to do some damage. When he swipes his arm, jump with the "X" button to avoid it.
Act 3 - 8: Pax in Bello
No. | Procedure |
---|---|
1 | Head to Dr. Octavius' Lab in Greenwich to trigger a cutscene |
2 | Boss Fight Phase 1: Damage Doctor Octopus |
3 | Boss Fight Phase 2: Stay in the air and damage Doctor Octopus |
4 | Boss Fight Phase 3: Defeat Doctor Octopus |
Defeat Doctor Octopus & Save New York City

Spider-Man must finally confront his former mentor as he falls from grace. Doctor Octopus offers a challenge with tentacle attacks, floors on fire, and thrown attacks as he stand between you and saving New York City.
Check Out the Doctor Octopus Boss Fight Guide2. Web Up Doctor Octopus' Arms to Create an Opening

Doctor Octopus is pretty agile with his arms so incapacitate him for a bit by webbing up his arms. Use △ once he is all web up to start a combo, but make sure to jump back in time to escape his attacks.
3. Keep Off Floor When Doctor Octopus Is Up The Tower

When Doctor Octopus climbs the tower, he sets the floor on fire, making it dangerous to step on it. Utilize your web-slinging moves and the "R2" button to swing above the floor & get to Doctor Octopus.
4. Follow Spider Sense To Know When To Dodge

Your Spider Sense will show up on-screen to indicate when Doctor Octopus will attack. Press the "◯" button to dodge & avoid damage.